Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 6/20 | 0.31 |
| ▸ | CNR1 | P21554 | 5/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631817 | 0.99 | THRA (0.33) | THRATHRBGPR84USP2S1PR2 | |
| SCHEMBL7635349 | 0.94 | THRA (0.37) | THRATHRBGPR84CNR2CNR1 | |
| SCHEMBL7635648 | 0.93 | THRA (0.35) | THRATHRBGPR84CNR2CNR1 | |
| SCHEMBL7635710 | 0.92 | GPR84 (0.36) | THRATHRBGPR84USP2HTT | |
| SCHEMBL7636825 | 0.91 | THRA (0.33) | THRATHRBGPR84S1PR2S1PR1 | |
| SCHEMBL7629430 | 0.91 | GPR84 (0.34) | THRATHRBGPR84USP2HTT | |
| SCHEMBL7629897 | 0.90 | CYP3A4 (0.32) | THRATHRB | |
| SCHEMBL7629203 | 0.88 | THRA (0.34) | THRATHRBGPR84S1PR2S1PR1 | |
| SCHEMBL7631624 | 0.86 | THRA (0.31) | THRATHRB | |
| SCHEMBL7632945 | 0.86 | THRA (0.32) | THRATHRBGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888270-B1 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-6140274-A | Dihalopropene compounds, their use as insecticides/acaricides and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0888270-A1 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997028112-A1 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-07 | — | — | WO | disclosed |