Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635349 | 0.99 | THRA (0.37) | THRATHRBCNR2CNR1PLA2G2A | |
| SCHEMBL7631817 | 0.94 | THRA (0.33) | THRATHRBGPR84 | |
| SCHEMBL7631089 | 0.93 | THRA (0.35) | THRATHRBCNR2CNR1LPAR1 | |
| SCHEMBL7637630 | 0.92 | CNR2 (0.38) | CNR2CNR1PLA2G2ALPAR1LPAR3 | |
| SCHEMBL7627671 | 0.91 | CNR2 (0.39) | CNR2CNR1LPAR1LPAR3GPR84 | |
| SCHEMBL7629897 | 0.90 | CYP3A4 (0.32) | THRATHRBMEN1ALDH1A1KMT2A | |
| SCHEMBL7636825 | 0.89 | THRA (0.33) | THRATHRBCNR2CNR1GPR84 | |
| SCHEMBL7632945 | 0.86 | THRA (0.32) | THRATHRBGPR84MEN1ALDH1A1 | |
| SCHEMBL7629430 | 0.86 | GPR84 (0.34) | THRATHRBCNR2CNR1LPAR1 | |
| SCHEMBL7629203 | 0.85 | THRA (0.34) | THRATHRBLPAR1LPAR3GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888270-B1 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-6140274-A | Dihalopropene compounds, their use as insecticides/acaricides and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0888270-A1 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997028112-A1 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-07 | — | — | WO | disclosed |