Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626839 | 0.84 | MEN1 (0.40) | MEN1KMT2APPARAPPARGPKM | |
| SCHEMBL7630706 | 0.80 | PKM (0.60) | PPARAPPARGPKM | |
| SCHEMBL2818377 | 0.79 | L3MBTL1 (0.53) | PPARAPPARGPKM | |
| SCHEMBL2815643 | 0.76 | PPARA (0.47) | PPARAPPARGPKM | |
| SCHEMBL7627580 | 0.72 | PPARG (0.47) | PPARAPPARGHDAC1HDAC2 | |
| SCHEMBL3686163 | 0.70 | ALDH1A1 (0.44) | PPARAPPARG | |
| SCHEMBL7625582 | 0.69 | PPARG (0.45) | PPARAPPARGHDAC1HDAC2 | |
| SCHEMBL5776738 | 0.69 | MAPT (0.50) | KMT2APPARA | |
| SCHEMBL3682169 | 0.69 | PPARG (0.39) | PPARAPPARG | |
| SCHEMBL2112969 | 0.69 | MAPT (0.47) | MEN1KMT2APPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350892-B1 | ENZYME INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2002-02-26 | — | — | US | disclosed |