SCHEMBL763149

CC(O)[C@H](N)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)C[C@H](C)Cc1ccc(O)cc1)C(C)C

nearest known ligand 0.59

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	4/20	0.59

▸	LNPEP	Q9UIQ6	7/20	0.59

▸	AGTR1	P30556	3/20	0.54

▸	AGTR2	P50052	3/20	0.54

▸	ANPEP	P15144	2/20	0.52

▸	SLC6A2	P23975	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15381910	0.93	REN (0.61)	RENLNPEPAGTR1AGTR2ANPEP
SCHEMBL15381926	0.89	REN (0.59)	RENLNPEPAGTR1AGTR2ANPEP
SCHEMBL13811917	0.82	NPY2R (0.58)	AGTR1AGTR2
SCHEMBL13811920	0.81	LNPEP (0.52)	RENLNPEPAGTR1AGTR2ANPEP
SCHEMBL29591343	0.79	SLC6A2 (0.63)	LNPEPANPEPSLC6A2
Angiotensin Iv SCHEMBL10066237	0.78	LNPEP (0.82)	RENLNPEPAGTR1AGTR2ANPEP
Angiotensin Iv SCHEMBL27169570	0.78	LNPEP (0.82)	RENLNPEPAGTR1AGTR2ANPEP
SCHEMBL29592580	0.78	SLC6A2 (0.60)	LNPEPSLC6A2
SCHEMBL31332003	0.78	REN (0.69)	RENLNPEPAGTR1AGTR2ANPEP
SCHEMBL29590802	0.77	SLC6A2 (0.63)	RENLNPEPANPEPSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8138140-B2	Self-assembling peptide amphiphiles and related methods for growth factor delivery	NORTHWESTERN UNIVERSITY (US)	2012-03-20	—	—	US	disclosed