SCHEMBL31332003

SCHEMBL31332003

CC(C)C(NC(=O)C1CCCN1C(=O)C(Cc1cnc[nH]1)NC(=O)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(NC(=O)CN)C(C)C)C(C)C)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
REN P00797 5/20 0.69
AGTR1 P30556 4/20 0.63
LNPEP Q9UIQ6 6/20 0.62
AGTR2 P50052 2/20 0.61
ANPEP P15144 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29532971 0.92 REN (0.67) RENAGTR1LNPEPAGTR2
SCHEMBL31332308 0.88 REN (0.64) RENAGTR1LNPEPAGTR2ANPEP
SCHEMBL29657514 0.83 REN (0.78) RENAGTR1AGTR2
SCHEMBL15336163 0.83 AGTR1 (0.71) RENAGTR1LNPEPAGTR2ANPEP
Angiotensin Iv SCHEMBL10066237 0.82 LNPEP (0.82) RENAGTR1LNPEPAGTR2ANPEP
Angiotensin Iv SCHEMBL27169570 0.82 LNPEP (0.82) RENAGTR1LNPEPAGTR2ANPEP
SCHEMBL29440860 0.82 SLC6A2 (0.62)
SCHEMBL29843115 0.82 REN (0.58) RENAGTR1LNPEPAGTR2
SCHEMBL29463333 0.81 AGTR2 (0.89) RENAGTR1AGTR2
Saralasin SCHEMBL24 0.81 AGTR1 (0.82) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR REN 580/4885AGTR1 51/4885LNPEP 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.