Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | NPY1R | P25929 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740844 | 0.91 | CHRM1 (0.50) | TLR8CHRM1HRH1ADORA2ANPY1R | |
| SCHEMBL740843 | 0.91 | CHRM1 (0.50) | TLR8CHRM1HRH1ADORA2ANPY1R | |
| SCHEMBL763158 | 0.81 | HRH1 (0.68) | TLR8CHRM1HRH1 | |
| SCHEMBL741172 | 0.79 | CHRM1 (0.50) | CHRM1HRH1NPY1R | |
| SCHEMBL741173 | 0.79 | CHRM1 (0.50) | CHRM1HRH1NPY1R | |
| SCHEMBL7045696 | 0.77 | CHRM1 (0.48) | CHRM1HRH1ADORA2ANPY1R | |
| SCHEMBL7044486 | 0.76 | CHRM1 (0.44) | CHRM1HRH1ADORA2ANPY1R | |
| SCHEMBL7043993 | 0.75 | CHRM1 (0.46) | CHRM1HRH1ADORA2ANPY1R | |
| SCHEMBL7041213 | 0.75 | CHRM1 (0.46) | CHRM1HRH1ADORA2ANPY1R | |
| SCHEMBL762531 | 0.75 | TLR8 (0.44) | TLR8CASRADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |