Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345706 | 0.85 | LMNA (0.53) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL7104388 | 0.82 | PGR (0.50) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL28302809 | 0.77 | TAAR1 (0.57) | LMNATAAR1ALDH1A1ADRA2AHTR2A | |
| SCHEMBL5711600 | 0.77 | PGR (0.50) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL27580073 | 0.77 | TAAR1 (0.52) | LMNATAAR1ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL6896248 | 0.75 | LMNA (0.47) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL11801689 | 0.74 | PGR (0.46) | LMNACES2CES1TDP1L3MBTL1 | |
| SCHEMBL25129603 | 0.74 | TAAR1 (0.48) | LMNATAAR1HSD17B10KMT2AKCNA3 | |
| SCHEMBL12445100 | 0.74 | GRM2 (0.49) | LMNATAAR1ALDH1A1KCNA3TSHR | |
| SCHEMBL1822406 | 0.74 | PGR (0.53) | LMNACES2CES1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451948-B1 | (METH)ACRYLATE COMPONENT; A THERMAL RESISTANCE-CONFERRING COMPONENT INCLUDING POLYMERIZABLE AROMATIC MATERIALS HAVING AT LEAST ONE CLAISEN REARRANGABLE FUNCTIONAL GROUP; AND (C) A RADICAL CURE-INDUCING COMPOSITION. | LOCTITE CORPORATION | 2002-09-17 | — | — | US | claimed |