Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289556 | 0.84 | PGR (0.53) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL1822406 | 0.84 | PGR (0.53) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL4944515 | 0.84 | PGR (0.46) | LMNAALDH1A1GAAPKMPGR | |
| SCHEMBL11801689 | 0.84 | PGR (0.46) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL5711600 | 0.84 | PGR (0.50) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL7104388 | 0.81 | PGR (0.50) | LMNAALDH1A1GAAPGRADRA2A | |
| SCHEMBL10345706 | 0.81 | LMNA (0.53) | LMNAALDH1A1PGRADRA2AADRA2B | |
| Benzoic Acid SCHEMBL560461 | 0.81 | TSHR (0.56) | LMNAALDH1A1GAAPKMPGR | |
| Benzoic Acid SCHEMBL28993296 | 0.81 | TSHR (0.56) | LMNAALDH1A1GAAPKMPGR | |
| SCHEMBL10382538 | 0.80 | GPR84 (0.47) | CES2CES1MMP2MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149242-B1 | 1-(2-HYDROXYARYL)-ALCAN-1-ONE OXIME, PREPARATION AND PHARMACEUTICAL USE | CHEMISCHE UND PHARMAZEUTISCHE FABRIKEN FAHLBERG-LIST GmbH (DE) | 1990-10-31 | — | — | EP | claimed |
| US-6828350-B1 | Inhibiting the activity of a picornavirus 3C protease or a cysteine protease with a composition having an orthohydroxy keto aryl core structure | EXEGENICS INC. | 2004-12-07 | — | — | US | disclosed |
| EP-1463493-A1 | METHODS OF INDUCING OVULATION-USING A NON-POLYPEPTIDE CAMP LEVEL MODULATOR | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003051344-A1 | METHODS OF INDUCING OVULATION_USING A NON-POLYPEPTIDE CAMP LEVEL MODULATOR | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-06-26 | — | — | WO | disclosed |
| EP-1035845-A1 | MODULATORS OF CYSTEINE PROTEASE | Arad, Dorit (IL) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999030699-A1 | MODULATORS OF CYSTEINE PROTEASE | ARAD DORIT (IL) | 1999-06-24 | — | — | WO | disclosed |
| EP-0149242-B1 | 1-(2-HYDROXYARYL)-ALCAN-1-ONE OXIME, PREPARATION AND PHARMACEUTICAL USE | CHEMISCHE UND PHARMAZEUTISCHE FABRIKEN FAHLBERG-LIST GmbH (DE) | 1990-10-31 | — | — | EP | disclosed |
| US-4816487-A | ANTIALLERGENS | HUMBOLDT-UNIVERSITAET ZU BERLIN (DD) | 1989-03-28 | — | — | US | disclosed |
| EP-0149242-A2 | 1-(2-Hydroxyaryl)-alcan-1-one oxime, preparation and pharmaceutical use | CHEMISCHE UND PHARMAZEUTISCHE FABRIKEN FAHLBERG-LIST GmbH (DE) | 1985-07-24 | — | — | EP | disclosed |