SCHEMBL7632453

SCHEMBL7632453

CCCC(c1ccc(O)cc1C(C)(C)CC)c1ccc(O)cc1C(C)(C)CC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 4/20 0.45
ALOX15 P16050 2/20 0.45
CYP2C19 P33261 2/20 0.45
TP53 P04637 1/20 0.45
CYP2D6 P10635 1/20 0.45
TYR P14679 3/20 0.38
HSD17B10 Q99714 2/20 0.38
NR1I2 O75469 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MIF P14174 1/20 0.38
HTT P42858 1/20 0.38
NFE2L2 Q16236 1/20 0.38
ESR1 P03372 4/20 0.33
ESR2 Q92731 3/20 0.33
FFAR1 O14842 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28806605 0.81 TYR (0.36) CYP2C9ALOX15TYRHSD17B10NR1I2
SCHEMBL27903499 0.80 CNR1 (0.37) ALOX15TP53TYRHSD17B10ALDH1A1
SCHEMBL1070210 0.76 ALOX15 (0.55) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL4596473 0.75 ALOX15 (0.49) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL4596678 0.75 TYR (0.50) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL3958496 0.75 TYR (0.48) CYP2C9ALOX15TYRHSD17B10NR1I2
SCHEMBL10620174 0.74 ALOX15 (0.51) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL27740837 0.73 CYP2C9 (0.48) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL30026979 0.73 ALDH1A1 (0.63) CYP2C9ALOX15TYRHSD17B10NR1I2
SCHEMBL133971 0.73 ALDH1A1 (0.63) CYP2C9ALOX15TYRHSD17B10NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2648191-B1 INSULATED WIRE AND CABLE FUJIKURA LTD (JP) 2019-02-13 EP claimed
US-20240043768-A1 PROCESS FOR PREPARING HOMO- AND COPOLYMERS OF ALKYL (METH)ACRYLATES WITH LOW RESIDUAL MONOMER CONTENT EVONIK OPERATIONS GMBH (DE) 2024-02-08 US disclosed
EP-1238012-A1 BLENDED POLYCARBONATE COMPOSITIONS Bayer Aktiengesellschaft (DE) 2002-09-11 EP disclosed
WO-2001030909-A1 BLENDED POLYCARBONATE COMPOSITIONS BAYER AKTIENGESELLSCHAFT (DE) 2001-05-03 WO disclosed
EP-0837086-A2 Copolycarbonate resin and resin composition comprising the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-04-22 EP disclosed
EP-0115940-B2 Film-forming propylene copolymer, film thereof and process for production of the film MITSUI PETROCHEMICAL IND (JP) 1997-03-19 EP disclosed
US-4983742-A BUTENE POLYMER OR COPOLYMER, INORGANIC HYDROXIDE, GRAFT-MODIFIED OLEFIN RESIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-01-08 US disclosed
US-4668753-A EHTYLENE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-05-26 US disclosed
EP-0115940-B1 FILM-FORMING PROPYLENE COPOLYMER, FILM THEREOF AND PROCESS FOR PRODUCTION OF THE FILM MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-12-30 EP disclosed
EP-0172961-A1 1-Butene polymer and its use MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-03-05 EP disclosed
EP-0131358-A1 Fire-retardant 1-butene resin composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-01-16 EP disclosed
EP-0115940-A1 Film-forming propylene copolymer, film thereof and process for production of the film MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-08-15 EP disclosed