Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PTGIR | P43119 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2439826 | 0.89 | ALOX15 (0.59) | PPARAALOX15FFAR1ALDH1A1PPARD | |
| SCHEMBL11332779 | 0.84 | ALOX15 (0.53) | PPARAALOX15FFAR1ALDH1A1PPARD | |
| SCHEMBL11544962 | 0.84 | ALOX15 (0.53) | PPARAALOX15FFAR1ALDH1A1PPARD | |
| SCHEMBL12611895 | 0.84 | ALDH1A1 (0.61) | PPARAALOX15ALDH1A1SMN1; SMN2PPARG | |
| Hydrochloric Acid SCHEMBL3179439 | 0.83 | ALOX15 (0.52) | PPARAALOX15FFAR1ALDH1A1PPARD | |
| SCHEMBL7565477 | 0.83 | FFAR1 (0.67) | LTA4HEPHX2PPARAFFAR1PPARD | |
| SCHEMBL2054507 | 0.83 | PPARA (0.67) | PPARAALDH1A1PPARG | |
| SCHEMBL8849741 | 0.81 | FFAR1 (0.67) | ALOX15FFAR1 | |
| SCHEMBL28669666 | 0.81 | ALOX15 (0.70) | PPARAALOX15FFAR1ALDH1A1PPARD | |
| SCHEMBL5696314 | 0.81 | PPARA (0.69) | PPARAALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350892-B1 | ENZYME INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2002-02-26 | — | — | US | disclosed |