Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14001892 | 0.86 | KMT2A (0.38) | PTGS2KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31162811 | 0.80 | ACHE (0.53) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL78687 | 0.80 | ACHE (0.53) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL12216137 | 0.79 | KCNJ1 (0.34) | PTGS2KDM4EMAPTSLC6A4PDE4D | |
| SCHEMBL12216149 | 0.79 | KMT2A (0.38) | KDM4EMAPTKMT2ASLC6A4PDE4D | |
| SCHEMBL941425 | 0.75 | ALDH1A1 (0.46) | PTGS2KDM4EALDH1A1ADORA3ADORA2A | |
| SCHEMBL16110979 | 0.75 | HTR2A (0.44) | KDM4EALDH1A1ADORA3ADORA2AMAPT | |
| SCHEMBL31119631 | 0.75 | HTR2A (0.44) | KDM4EALDH1A1ADORA3ADORA2AMAPT | |
| SCHEMBL8285651 | 0.73 | TIPARP (0.40) | KDM4ESMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL11805157 | 0.73 | MRGPRX4 (0.52) | PTGS2KDM4EALDH1A1ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911320-B1 | 1,2-Di-substituted benzenecarboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-6114325-A | 1,2-di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0911320-A2 | 1,2-Di-substituted benzenecarboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 1999-04-28 | — | — | EP | disclosed |
| US-4952721-A | AIR OXIDATION WITH HEAVY METAL CATALYSTS | AMOCO CORPORATION (US) | 1990-08-28 | — | — | US | disclosed |