Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16111006 | 0.83 | TIPARP (0.41) | TIPARPKCNJ1KCNH2KEAP1MAOA | |
| SCHEMBL16110979 | 0.81 | HTR2A (0.44) | KCNJ1KCNH2MAOAMAOBMEN1 | |
| SCHEMBL31119631 | 0.81 | HTR2A (0.44) | KCNJ1KCNH2MAOAMAOBMEN1 | |
| SCHEMBL28346647 | 0.76 | ABCB1 (0.53) | TIPARPHTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL31162811 | 0.75 | ACHE (0.53) | LMNAKCNJ1MAOBKDM4EMAPK14 | |
| SCHEMBL78687 | 0.75 | ACHE (0.53) | LMNAKCNJ1MAOBKDM4EMAPK14 | |
| SCHEMBL7632703 | 0.73 | PTGS2 (0.47) | HTTLMNAKCNJ1SMN1; SMN2MAOB | |
| SCHEMBL7110196 | 0.71 | MAOA (0.42) | KCNJ1KCNH2MAOAMAOBKDM4E | |
| SCHEMBL17305579 | 0.71 | KCNA3 (0.59) | HTTSMN1; SMN2MAOAMEN1KMT2A | |
| SCHEMBL27987728 | 0.71 | ALOX5 (0.50) | KCNJ1KCNH2MAOAMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1707202-A1 | Organic compounds | Speedel Experimenta AG (CH) | 2006-10-04 | — | — | EP | disclosed |
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |