Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 6/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637631 | 0.98 | FAAH (0.55) | FAAHLTA4HS1PR4S1PR1S1PR3 | |
| SCHEMBL7626715 | 0.97 | FAAH (0.54) | FAAHLTA4HS1PR4S1PR1S1PR3 | |
| SCHEMBL3488458 | 0.89 | FAAH (0.65) | FAAHS1PR4S1PR1S1PR3LMNA | |
| SCHEMBL3487635 | 0.89 | FAAH (0.65) | FAAHS1PR4S1PR1S1PR3LMNA | |
| SCHEMBL7632104 | 0.88 | FAAH (0.55) | FAAHS1PR4S1PR1S1PR3THRA | |
| SCHEMBL7630829 | 0.86 | FAAH (0.53) | FAAHTHRATHRB | |
| SCHEMBL7632715 | 0.86 | FAAH (0.53) | FAAHS1PR4S1PR1S1PR3THRA | |
| SCHEMBL7625591 | 0.85 | LMNA (0.66) | LTA4HS1PR4S1PR1S1PR3LMNA | |
| SCHEMBL7629447 | 0.85 | FAAH (0.55) | FAAHS1PR4S1PR1S1PR3THRA | |
| SCHEMBL7629103 | 0.84 | LMNA (0.51) | FAAHS1PR4S1PR1S1PR3THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350892-B1 | ENZYME INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2002-02-26 | — | — | US | disclosed |
| US-6255496-B1 | CYTOSOLIC PHOSPHATIDE 2-ACYLHYDROLASE ENZYME INHIBITORS; CONTROLLING INFLAMMATORY DISEASES | BRISTOL-MYERS SQUIBB COMPANY | 2001-07-03 | — | — | US | disclosed |