Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14518618 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL6804932 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL7150972 | 0.78 | AKR1C3 (0.59) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL15709853 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRAKR1C3FBP1AKR1C1 | |
| SCHEMBL19712515 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRAKR1C3FBP1AKR1C1 | |
| SCHEMBL23458002 | 0.78 | AKR1C3 (0.73) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL466536 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRAKR1C3FBP1AKR1C1 | |
| SCHEMBL6433811 | 0.78 | AKR1C3 (0.73) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL60657 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL598776 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TSHRAKR1C3FBP1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114200-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114198-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| EP-1209154-A1 | Preparation of monofluoroalkenes | Aventis CropScience GmbH (DE) | 2002-05-29 | — | — | EP | disclosed |
| WO-2002040459-A1 | PREPARATION OF MONOFLUOROALKENES | BAYER CROPSCIENCE GMBH (DE) | 2002-05-23 | — | — | WO | disclosed |
| US-5478964-A | N-fluorosulfonimides and their application as fluorinating agents | ALLIED-SIGNAL INC. (US) | 1995-12-26 | — | — | US | disclosed |
| US-5254732-A | N-fluorosulfonimides and their application as fluorinating agents | ALLIED-SIGNAL INC. (US) | 1993-10-19 | — | — | US | disclosed |