Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14518618 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL7633159 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL7150972 | 0.78 | AKR1C3 (0.59) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL15709853 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRAKR1C3FBP1AKR1C1 | |
| SCHEMBL19712515 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRAKR1C3FBP1AKR1C1 | |
| SCHEMBL23458002 | 0.78 | AKR1C3 (0.73) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL466536 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TSHRAKR1C3FBP1AKR1C1 | |
| SCHEMBL6433811 | 0.78 | AKR1C3 (0.73) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL60657 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL598776 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TSHRAKR1C3FBP1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723743-B1 | TREATING PATIENT SUFFERING FROM RHEUMATOID ARTHRITIS, PSORIASIS, BRONCHIAL ASTHMA, ALZHEIMER'S DISEASE, MYOCARDIAL INFARCTION OR ATHEROSCLEROSIS | NEUROGEN CORPORATION | 2004-04-20 | — | — | US | claimed |
| US-6080819-A | Blends of olefin polymers and syndiotactic vinyl polymers | BOREALIS AG (AT) | 2000-06-27 | — | — | US | claimed |
| CN-110462715-A | The manufacturing method of heat-shrinkable label, package body and heat-shrinkable label | TOYO BOSEKI | 2019-11-15 | — | — | CN | disclosed |
| CN-109071840-A | Molding material, sheet molding compound, and fiber-reinforced composite material | 三菱化学株式会社 | 2018-12-21 | — | — | CN | disclosed |
| CN-108794308-A | 1,2,3,4- tetralin quasi-compounds and its preparation method and application | 北京大学深圳研究生院 | 2018-11-13 | — | — | CN | disclosed |
| US-20180086684-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | ASAHI GLASS COMPANY, LIMITED (JP) | 2018-03-29 | — | — | US | disclosed |
| CN-107614555-A | Method for producing thermoplastic elastomer and thermoplastic elastomer | 株式会社钟化 | 2018-01-19 | — | — | CN | disclosed |
| US-9796647-B2 | Method for producing fluorine-containing olefin | ASAHI GLASS COMPANY, LIMITED (JP) | 2017-10-24 | — | — | US | disclosed |
| US-20170101360-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | ASAHI GLASS COMPANY, LIMITED (JP) | 2017-04-13 | — | — | US | disclosed |
| US-9598335-B2 | Method for producing fluorine-containing olefin | ASAHI GLASS COMPANY, LIMITED (JP) | 2017-03-21 | — | — | US | disclosed |
| US-20160176791-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | ASAHI GLASS COMPANY, LIMITED (JP) | 2016-06-23 | — | — | US | disclosed |
| WO-2002040459-A1 | PREPARATION OF MONOFLUOROALKENES | BAYER CROPSCIENCE GMBH (DE) | 2002-05-23 | — | — | WO | disclosed |
| US-6080819-A | Blends of olefin polymers and syndiotactic vinyl polymers | BOREALIS AG (AT) | 2000-06-27 | — | — | US | disclosed |
| CN-1251594-A | Method for producing fluoropolymer | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2000-04-26 | — | — | CN | disclosed |
| EP-0884356-A2 | Blends of polyolefins and syndiotactic vinyl polymeres | PCD Polymere AG (AT) | 1998-12-16 | — | — | EP | disclosed |
| US-5478964-A | N-fluorosulfonimides and their application as fluorinating agents | ALLIED-SIGNAL INC. (US) | 1995-12-26 | — | — | US | disclosed |
| US-5326489-A | Sulfonated polymer | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0523300-B1 | Electrorheological fluids | NIPPON CATALYTIC CHEM IND (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-5254732-A | N-fluorosulfonimides and their application as fluorinating agents | ALLIED-SIGNAL INC. (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0523300-A1 | Electrorheological fluids | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086684-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | FOS, CYP2F1, CYP4F11 | ALDH1A1 607/4885TSHR 1612/4885AKR1C3 900/4885 |
| US-20170101360-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | FOS, CYP2F1, CYP4F11 | ALDH1A1 607/4885TSHR 1612/4885AKR1C3 900/4885 |
| US-20160176791-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | FOS, CYP2F1, CYP4F11 | ALDH1A1 607/4885TSHR 1612/4885AKR1C3 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.