SCHEMBL466536

SCHEMBL466536

FC(F)=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TSHR P16473 2/20 0.46
AKR1C3 P42330 1/20 0.46
AKR1C1 Q04828 1/20 0.44
ESR1 P03372 1/20 0.44
FBP1 P09467 3/20 0.41
MAOB P27338 1/20 0.41
CYP2A6 P11509 1/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
NFE2L2 Q16236 1/20 0.40
PRMT1 Q99873 1/20 0.40
LMNA P02545 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MCL1 Q07820 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL30208210 0.92 AKR1C3 (0.52) ALDH1A1TSHRAKR1C3AKR1C1FBP1
SCHEMBL26604330 0.85 TP53 (0.57) ALDH1A1CYP3A4LMNA
SCHEMBL19712514 0.82 ALDH1A1 (0.46) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL19712515 0.82 ALDH1A1 (0.46) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL15709853 0.82 ALDH1A1 (0.46) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL16590761 0.80 NFE2L2 (0.39) FBP1CYP3A4NFE2L2
SCHEMBL28933412 0.79 LTA4H (0.50) ALDH1A1TSHRMAOBLMNAL3MBTL1
SCHEMBL14518618 0.78 ALDH1A1 (0.54) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL1791248 0.78 ALDH1A1 (0.43) ALDH1A1TSHRAKR1C3AKR1C1ESR1
SCHEMBL14549093 0.78 MCL1 (0.45) ALDH1A1TSHRAKR1C3AKR1C1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 830 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6352782-B1 None US claimed
CN-118373733-A Difluorostyrene-containing derivative and preparation method and application thereof 上海应用技术大学 2024-07-23 CN claimed
CN-117954593-A Modified positive electrode material and preparation method and application thereof 深圳市德方纳米科技股份有限公司 2024-04-30 CN claimed
CN-111979629-B Processing method of special carbon fiber fabric for special clothing 安徽宜民服饰股份有限公司 2023-08-25 CN claimed
WO-2023050503-A1 GAS SEPARATION MEMBRANE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 常熟三爱富中昊化工新材料有限公司 2023-04-06 WO claimed
CN-113563328-B Preparation method of 1, 3-disubstituted-2-fluoro indolizine derivative 台州学院 2022-07-05 CN claimed
US-11345788-B2 Porous sheet, and porous composite KURARAY PLASTICS CO., LTD. (JP) 2022-05-31 US claimed
CN-113786743-A Gas separation membrane, method for producing same and use thereof 常熟三爱富中昊化工新材料有限公司 2021-12-14 CN claimed
CN-113563328-A Preparation method of 1, 3-disubstituted-2-fluoro indolizine derivative 台州学院 2021-10-29 CN claimed
CN-113380990-A Lithium ion battery composite positive electrode material, preparation method thereof and lithium ion battery 郑州宇通集团有限公司 2021-09-10 CN claimed
US-20140205822-A1 WIDE-VIEW OPTICAL FILM HAVING REVERSED WAVELENGTH DISPERSION AKRON POLYMER SYSTEMS, INC. (US) 2014-07-24 US claimed
EP-2619255-A2 OPTICAL COMPENSATION FILMS BASED ON FLUOROPOLYMERS Akron Polymer Systems, Inc. (US) 2013-07-31 EP claimed
US-20120181295-A1 CONTAINER STOPPER COMPRISING FOAM-MOLDED ARTICLE KURARAY CO., LTD. (JP) 2012-07-19 US claimed
WO-2012040366-A2 OPTICAL COMPENSATION FILMS BASED ON FLUOROPOLYMERS AKRON POLYMER SYSTEMS, INC. (US) 2012-03-29 WO claimed
US-20110076487-A1 OPTICAL COMPENSATION FILMS BASED ON FLUOROPOLYMERS AKRON POLYMER SYSTEMS, INC. 2011-03-31 US claimed
EP-1834975-A1 Poly(Phenylene ether) - Polyvinyl thermosetting resin General Electric Company (US) 2007-09-19 EP claimed
EP-1421125-A1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS INC. (CA) 2004-05-26 EP claimed
WO-2003018654-A1 PROCESS FOR PREPARING GRAFT COPOLYMER MEMBRANES BALLARD POWER SYSTEMS INC. (CA) 2003-03-06 WO claimed
US-6352782-B2 REACTING A POLYPHENYLENE ETHER CONTAINING HYDROXY GROUPS THAT HAVE BEEN CAPPED WITH A COMPOUND CONTAINING ETHYLENICALLY UNSATURATION WITH A CURABLE UNSATURATED MONOMER CAPABLE OF REACTING WITH ETHYLENICALLY UNSATURATED COMPOUND GENERAL ELECTRIC COMPANY 2002-03-05 US claimed
US-5213938-A Oxidation of toner compositions XEROX CORPORATION (US) 1993-05-25 US claimed