Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.50 |
| ▸ | MEN1 | O00255 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7633195 | 1.00 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL14537132 | 0.87 | POLB (0.57) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL14515516 | 0.80 | KMT2A (0.38) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL6706301 | 0.80 | ERN1 (0.49) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL10040967 | 0.78 | L3MBTL1 (0.44) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL10040968 | 0.78 | L3MBTL1 (0.44) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL13295289 | 0.77 | KMT2A (0.36) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL38660603 | 0.77 | KMT2A (0.36) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL14337279 | 0.74 | KMT2A (0.47) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL14537133 | 0.73 | MEN1 (0.52) | KMT2AMEN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020188123-A1 | Polydentate asymmetric ligands based on binaphthyl | DEGUSSA AG (DE) | 2002-12-12 | — | — | US | disclosed |
| EP-1256570-A1 | Polydentate asymmetric ligands based on biphenyl | Degussa AG (DE) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020188123-A1 | Polydentate asymmetric ligands based on binaphthyl | MT-ND4L, DNM1L, GNE | KMT2A 1238/4885MEN1 3184/4885ALDH1A1 1097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.