SCHEMBL10040967

SCHEMBL10040967

Oc1c(/C=N/[C@H]2CCCC[C@@H]2/N=C/c2cc3ccccc3c(-c3c(-c4ccccc4)ccc4ccccc34)c2O)cc2ccccc2c1-c1c(-c2ccccc2)ccc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.44
MAPT P10636 8/20 0.39
ALDH1A1 P00352 5/20 0.39
MPI P34949 2/20 0.39
KMT2A Q03164 8/20 0.38
MEN1 O00255 6/20 0.38
HPGD P15428 4/20 0.38
KDM4E B2RXH2 3/20 0.38
GPR84 Q9NQS5 3/20 0.33
CACNA1B Q00975 1/20 0.32
POLB P06746 3/20 0.31
THRB P10828 2/20 0.31
GAA P10253 1/20 0.31
BLM P54132 1/20 0.31
CASP6 P55212 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
TDP2 O95551 1/20 0.31
RECQL P46063 1/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10040968 1.00 L3MBTL1 (0.44) L3MBTL1MAPTALDH1A1MPIKMT2A
SCHEMBL10040972 0.86 L3MBTL1 (0.33) L3MBTL1MAPTALDH1A1MPI
SCHEMBL10300871 0.86 L3MBTL1 (0.33) L3MBTL1MAPTALDH1A1MPI
SCHEMBL10040974 0.86 L3MBTL1 (0.33) L3MBTL1MAPTALDH1A1MPI
SCHEMBL7633196 0.78 KMT2A (0.50) L3MBTL1MAPTALDH1A1MPIKMT2A
SCHEMBL7633195 0.78 KMT2A (0.50) L3MBTL1MAPTALDH1A1MPIKMT2A
SCHEMBL14515516 0.77 KMT2A (0.38) MAPTALDH1A1MPIKMT2AMEN1
SCHEMBL6706301 0.77 ERN1 (0.49) MAPTALDH1A1MPIKMT2AMEN1
SCHEMBL14804453 0.75 ALOX5 (0.43) L3MBTL1MAPTALDH1A1MPIKMT2A
SCHEMBL14765562 0.74 ANPEP (0.31) MAPTALDH1A1MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8410295-B2 Method for production of optically active epoxy compound, and complex used therefor and process for producing the same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2013-04-02 US disclosed
US-8410295-B2 Method for production of optically active epoxy compound, and complex used therefor and process for producing the same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2013-04-02 US disclosed
US-20120178954-A1 METHOD FOR PRODUCTION OF OPTICALLY ACTIVE EPOXY COMPOUND, AND COMPLEX USED THEREFOR AND PROCESS FOR PRODUCING THE SAME JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-07-12 US disclosed
US-20120178954-A1 METHOD FOR PRODUCTION OF OPTICALLY ACTIVE EPOXY COMPOUND, AND COMPLEX USED THEREFOR AND PROCESS FOR PRODUCING THE SAME JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-07-12 US disclosed
US-8163941-B2 Reacting an unsaturated compound with oxidier in presence of a oxidation catalyst JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-04-24 US disclosed
US-8163941-B2 Reacting an unsaturated compound with oxidier in presence of a oxidation catalyst JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-04-24 US disclosed
US-20080071099-A1 Method for Production of Optically Active Epoxy Compound, and Complex Used Therefor and Process for Producing the Same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2008-03-20 US disclosed
US-20080071099-A1 Method for Production of Optically Active Epoxy Compound, and Complex Used Therefor and Process for Producing the Same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2008-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080071099-A1 Method for Production of Optically Active Epoxy Compound, and Complex Used Therefor and Process for Producing the Same EPRS1, PPOX, POR L3MBTL1 3054/4885MAPT 4881/4885ALDH1A1 840/4885
US-20120178954-A1 METHOD FOR PRODUCTION OF OPTICALLY ACTIVE EPOXY COMPOUND, AND COMPLEX USED THEREFOR AND PROCESS FOR PRODUCING THE SAME CYP4F11, CYP51A1, COASY L3MBTL1 3098/4885MAPT 4823/4885ALDH1A1 2091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.