Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17633584 | 0.85 | TOP2A (0.47) | TOP2ATOP2BALDH1A1GAAPKM | |
| SCHEMBL477320 | 0.84 | CNR2 (0.58) | GAACYP1A2CYP2C19CNR2MAPT | |
| SCHEMBL6948270 | 0.81 | CNR2 (0.55) | ALDH1A1GAAPKMHPGDCNR2 | |
| SCHEMBL13127055 | 0.80 | CNR2 (0.57) | ALDH1A1CYP2D6HPGDCNR2MAPT | |
| SCHEMBL22867983 | 0.80 | LMNA (0.51) | GAACNR2MAPTL3MBTL1TDP1 | |
| SCHEMBL15192487 | 0.79 | ALDH1A1 (0.50) | TOP2ATOP2BALDH1A1GAAPKM | |
| SCHEMBL22420293 | 0.77 | CNR2 (0.54) | ALDH1A1GAACYP1A2HPGDCYP2C19 | |
| SCHEMBL11863667 | 0.77 | CNR2 (0.47) | TOP2ATOP2BALDH1A1GAAPKM | |
| SCHEMBL2782524 | 0.77 | CNR2 (0.54) | ALDH1A1GAACNR2MAPTL3MBTL1 | |
| SCHEMBL10358703 | 0.76 | AKR1C3 (0.49) | GAACNR2L3MBTL1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224195-A1 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001027128-A1 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |