SCHEMBL7633259

SCHEMBL7633259

[CH2]COCCOC[C](OOC(=O)c1ccc(OC)cc1)OOC(=O)c1ccc(OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
ESR2 Q92731 1/20 0.43
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
MAPT P10636 7/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GSK3B P49841 1/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7630120 0.93 CA1 (0.50) CA1CA2ESR2CES2CES1
SCHEMBL7627600 0.86 ALDH1A1 (0.45) MAPTRAB9ANPC1KMT2ALMNA
SCHEMBL7628033 0.86 L3MBTL1 (0.37) MAPTRAB9ASMN1; SMN2NPC1MEN1
SCHEMBL7625463 0.86 TDP1 (0.42) CES2CES1MAPTRAB9ASMN1; SMN2
SCHEMBL7623959 0.85 KMT2A (0.44) MAPTRAB9ASMN1; SMN2NPC1KMT2A
SCHEMBL7630724 0.85 L3MBTL1 (0.46) MAPTRAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL7635344 0.85 RARB (0.47) MAPTKMT2AALDH1A1GAA
SCHEMBL7627324 0.84 ALDH1A1 (0.41) MAPTRAB9ASMN1; SMN2NPC1MEN1
SCHEMBL7632007 0.84 CES2 (0.47) ESR2CES2CES1MAPTRAB9A
SCHEMBL7625731 0.83 MAPT (0.50) CA1CA2MAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed