Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Inosine SCHEMBL15903470 | 1.00 | PAX8 (0.57) | PAX8HPGDLMNATP53ALDH1A1 | |
| Inosine SCHEMBL20138538 | 1.00 | PAX8 (0.57) | PAX8HPGDLMNATP53ALDH1A1 | |
| Inosine SCHEMBL1682742 | 1.00 | PAX8 (0.57) | PAX8HPGDLMNATP53ALDH1A1 | |
| Inosine SCHEMBL568027 | 1.00 | PAX8 (0.57) | PAX8HPGDLMNATP53ALDH1A1 | |
| SCHEMBL21063147 | 0.90 | LMNA (0.47) | PAX8HPGDLMNATP53ALDH1A1 | |
| Inosine SCHEMBL15348254 | 0.89 | SLC29A1 (0.57) | PAX8LMNAALDH1A1PMP22ADORA3 | |
| Inosine SCHEMBL14126094 | 0.89 | SLC29A1 (0.57) | PAX8LMNAALDH1A1PMP22ADORA3 | |
| Adenosine SCHEMBL29840889 | 0.86 | ADORA2A (0.52) | PAX8HPGDLMNATP53ALDH1A1 | |
| Thioinosine SCHEMBL29988995 | 0.85 | ALDH1A1 (0.66) | PAX8HPGDLMNATP53ALDH1A1 | |
| Thioinosine SCHEMBL18314189 | 0.85 | ALDH1A1 (0.66) | PAX8HPGDLMNATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160312261-A1 | ENZYMATIC PRODUCTION OF CYTOSINIC NUCLEOSIDE ANALOGUES | PLASMIA BIOTECH, S.L. (ES) | 2016-10-27 | — | — | US | disclosed |
| EP-2883959-A1 | Enzymatic production of cytosinic nucleoside analogues | Plasmia Biotech, S.L. (ES) | 2015-06-17 | — | — | EP | disclosed |
| US-6455506-B1 | Lyxofuranosyl benzimidazoles as antiviral agents | SMITHKLINE BEECHAM CORPORATION | 2002-09-24 | — | — | US | disclosed |
| EP-1000080-A1 | LYXOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | The Regents of The University of Michigan (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999051619-A1 | ARABINOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-10-14 | — | — | WO | disclosed |
| WO-1999006424-A1 | LYXOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-02-11 | — | — | WO | disclosed |