Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 3/20 | 0.38 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7630394 | 0.91 | RAB9A (0.48) | RAB9ACYSLTR2CYSLTR1PLK1PLK3 | |
| SCHEMBL7627971 | 0.86 | RAB9A (0.46) | RAB9AITGB3ITGA2BHTR1FMAPT | |
| SCHEMBL7631342 | 0.81 | RAB9A (0.42) | RAB9APLK1PLK3MTNR1AMTNR1B | |
| SCHEMBL7626468 | 0.79 | GPR35 (0.56) | CYSLTR2CYSLTR1 | |
| SCHEMBL7633140 | 0.79 | HSD17B13 (0.38) | RAB9ACYSLTR2CYSLTR1PLK1PLK3 | |
| SCHEMBL7626547 | 0.79 | RAB9A (0.47) | RAB9AHTR1FLMNAMAPT | |
| SCHEMBL7629779 | 0.79 | RAB9A (0.52) | RAB9ALMNAMAPT | |
| SCHEMBL7632498 | 0.78 | TDP1 (0.44) | ITGB3ITGA2BLMNAMAPT | |
| SCHEMBL7626734 | 0.78 | MTNR1A (0.40) | MTNR1AMTNR1B | |
| SCHEMBL7636279 | 0.77 | MTNR1A (0.47) | MTNR1AMTNR1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-B1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2002-06-12 | — | — | EP | disclosed |
| US-5990142-A | ANTIINFLAMMATORY AGENTS AND ANTIALLERGENS HAVING GOOD ORAL ADSORPTION AND BIOAVAILABILITY; CARDIOTONIC AND ANTIISCHEMIC AGENTS | LABORATORIOS MENARINI S.A. (ES) | 1999-11-23 | — | — | US | disclosed |
| EP-0888327-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034885-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-09-25 | — | — | WO | disclosed |