Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 known ✓ | P25103 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7640663 | 0.96 | TACR1 (0.32) | TACR1 | |
| Hydrochloric Acid SCHEMBL7645207 | 0.96 | HTR1A (0.30) | — | |
| Hydrochloric Acid SCHEMBL6923408 | 0.87 | DRD2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6924009 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL7639533 | 0.79 | CNR1 (0.35) | TACR1 | |
| Hydrochloric Acid SCHEMBL7647410 | 0.78 | TACR1 (0.32) | TACR1 | |
| Hydrochloric Acid SCHEMBL6290544 | 0.75 | CNR1 (0.35) | TACR1 | |
| Hydrochloric Acid SCHEMBL7642826 | 0.73 | TACR1 (0.32) | TACR1 | |
| Hydrochloric Acid SCHEMBL7637530 | 0.73 | — | — | |
| SCHEMBL6930680 | 0.71 | CNR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479685-B2 | POLYMERIZING ETHYLENE AND ANOTHER ALPHA-OLEFIN IN THE PRESENCE OF AN UNBRIDGED, ROTATING, NON-RIGID FLUXIONAL METALLOCENE CATALYST COMPONENT AND A CO-CATALYST | THE BOARD OF TRUSTEES OF THE LELAND STANDARD JUNIOR UNIVERSITY | 2002-11-12 | — | — | US | disclosed |
| US-6380341-B1 | A COPOLYMER OF ETHYLENE WITH AT LEAST ONE COMONOMER CONTAINING AT LEAST 4 CARBON ATOMS, BEING CHARACTERIZED BY A POLYDISPERSITY GREATER THAN 2, A BROAD MELTING POINT RANGE HAVING MULTIPLE MELTING POINT PEAKS | THE BOARD OF TRUSTEES OF LELAND STANFORD JR. UNIVERSITY | 2002-04-30 | — | — | US | disclosed |