Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631027 | 0.93 | NPC1 (0.47) | NPC1RAB9ATDP1PARP1MEN1 | |
| SCHEMBL7632007 | 0.85 | CES2 (0.47) | NPC1RAB9APARP1MAPTMEN1 | |
| SCHEMBL7625463 | 0.83 | TDP1 (0.42) | NPC1RAB9ATDP1MAPTPOLB | |
| SCHEMBL7627403 | 0.83 | LMNA (0.53) | NPC1RAB9ATDP1L3MBTL1MAPT | |
| SCHEMBL7628767 | 0.83 | KMO (0.42) | NPC1RAB9ATDP1MAPTHDAC8 | |
| SCHEMBL7626336 | 0.83 | KMT2A (0.44) | NPC1RAB9AL3MBTL1MAPTMEN1 | |
| SCHEMBL7630307 | 0.82 | PARP1 (0.47) | NPC1RAB9ATDP1PARP1MAPT | |
| SCHEMBL7628461 | 0.79 | PARP1 (0.45) | NPC1RAB9ATDP1PARP1MAPT | |
| SCHEMBL7626962 | 0.79 | PARP1 (0.40) | NPC1RAB9ATDP1PARP1L3MBTL1 | |
| SCHEMBL7627785 | 0.79 | TDP1 (0.38) | NPC1RAB9ATDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233014-A1 | ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME | NOF CORPORATION (JP) | 2002-08-21 | — | — | EP | disclosed |