Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 10/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638126 | 0.93 | GPR35 (0.45) | GPR35GPR55RAB9ACYSLTR2CYSLTR1 | |
| SCHEMBL7632445 | 0.90 | GPR35 (0.54) | GPR35GPR55 | |
| SCHEMBL7632402 | 0.89 | GPR35 (0.46) | GPR35GPR55RAB9A | |
| SCHEMBL7630922 | 0.86 | GPR35 (0.49) | GPR35GPR55RAB9A | |
| SCHEMBL7627975 | 0.83 | CYSLTR2 (0.41) | GPR35CYSLTR2CYSLTR1 | |
| SCHEMBL7625167 | 0.83 | GPR35 (0.57) | GPR35GPR55 | |
| SCHEMBL7633292 | 0.82 | GPR35 (0.44) | GPR35GPR55RAB9ACYSLTR2CYSLTR1 | |
| SCHEMBL7634224 | 0.82 | GPR35 (0.49) | GPR35GPR55RAB9ACYSLTR2CYSLTR1 | |
| SCHEMBL7630341 | 0.80 | PRKDC (0.41) | — | |
| SCHEMBL7630340 | 0.80 | PRKDC (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-B1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2002-06-12 | — | — | EP | disclosed |
| US-5990142-A | ANTIINFLAMMATORY AGENTS AND ANTIALLERGENS HAVING GOOD ORAL ADSORPTION AND BIOAVAILABILITY; CARDIOTONIC AND ANTIISCHEMIC AGENTS | LABORATORIOS MENARINI S.A. (ES) | 1999-11-23 | — | — | US | disclosed |
| EP-0888327-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034885-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-09-25 | — | — | WO | disclosed |