SCHEMBL7635761

SCHEMBL7635761

Cc1ccc(OC(=O)C(C)(C)C)c(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ELANE P08246 10/20 0.49
MRGPRX4 Q96LA9 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
CYP3A4 P08684 1/20 0.41
HIF1A Q16665 1/20 0.41
ADRB2 P07550 1/20 0.40
PPARG P37231 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22251584 0.83 ACHE (0.57) ELANEALDH1A1LMNACYP3A4HIF1A
SCHEMBL11137359 0.82 MRGPRX4 (0.47) MRGPRX4KDM4EALDH1A1PPARGCYP2C9
SCHEMBL12773409 0.81 KMT2A (0.55) ELANEALDH1A1LMNACYP3A4HIF1A
SCHEMBL11609948 0.80 KDM4E (0.48) MRGPRX4KDM4EALDH1A1PPARGCYP2C9
SCHEMBL8367844 0.80 ALDH1A1 (0.49) MRGPRX4KDM4EALDH1A1LMNACYP3A4
SCHEMBL9309156 0.79 ABL1 (0.50) ELANEKDM4EALDH1A1LMNACYP3A4
SCHEMBL28530702 0.79 ACHE (0.45) MRGPRX4KDM4EALDH1A1PPARGCYP2C9
SCHEMBL22425672 0.78 ELANE (0.50) ELANEALDH1A1LMNACYP3A4HIF1A
SCHEMBL7628046 0.78 ELANE (0.45) ELANEALDH1A1LMNACYP3A4HIF1A
SCHEMBL26972869 0.77 ELANE (0.46) ELANEKDM4EALDH1A1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0754683-B1 ETHER COMPOUND, USE THEREOF, AND INTERMEDIATE FOR PRODUCING THE COMPOUND SUMITOMO CHEMICAL CO (JP) 2002-08-14 EP disclosed
CN-1079794-C Ether compound, use thereof, and intermediate for producing the compound SUMITOMO CHEM IND (JP) 2002-02-27 CN disclosed
US-5972949-A COMPOUNDS SUCH AS 4-(1-PYRAZOLYL)METHYLPHENYL 2-(2-PYRIMIDYLOXY) ETHYL ETHER; INSECTICIDAL AND/OR ACARICIDAL AGENTS SUMITO CHEMICAL CO., LTD. (JP) 1999-10-26 US disclosed
US-5883262-A INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-16 US disclosed
US-5684022-A ANTIFERTILITY AGENT PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-11-04 US disclosed
CN-1149289-A Ether compounds, their use and intermediates for their preparation SUMITOMO CHEMICAL CO (JP) 1997-05-07 CN disclosed
EP-0757048-A1 ETHER COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-02-05 EP disclosed
EP-0754683-A1 ETHER COMPOUND, USE THEREOF, AND INTERMEDIATE FOR PRODUCING THE COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-01-22 EP disclosed