SCHEMBL7635975

SCHEMBL7635975

C=CCC(CC=C)(OCC(=O)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37
CTH P32929 1/20 0.32
CBS P35520 1/20 0.32
THPO P40225 1/20 0.32
HTT P42858 1/20 0.32
THRB P10828 1/20 0.31
ABCC4 O15439 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27595253 0.81 ALDH1A1 (0.36) TSHRALDH1A1HTT
SCHEMBL27851632 0.79 ALDH1A1 (0.35) TSHRALDH1A1HTT
SCHEMBL2282279 0.75 ALDH1A1 (0.40) TSHRALDH1A1CTHCBSTHPO
SCHEMBL9052371 0.74 ALDH1A1 (0.34) TSHRALDH1A1
SCHEMBL8223321 0.74 ALDH1A1 (0.34) TSHRALDH1A1
SCHEMBL28772080 0.73 ALDH1A1 (0.39) TSHRALDH1A1CTHCBSTHPO
SCHEMBL8371321 0.73 ALDH1A1 (0.39) TSHRALDH1A1CTHCBSTHPO
SCHEMBL28427067 0.73 FFAR3 (0.35) TSHRALDH1A1CTHCBSTHPO
SCHEMBL370518 0.71 ALOX15 (0.33)
SCHEMBL461545 0.71 ALDH1A1 (0.33) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0783710-B1 POLYESTER RESIN-BASED HIGH INDEX OPHTHALMIC LENSES HAVING IMPROVED OPTICAL UNIFORMITY AND/OR TINTABILITY SIGNET ARMORLITE INC (US) 2002-05-29 EP claimed
EP-0065476-B1 COMPOSITE OF RUBBER AND METAL REINFORCEMENT THEREFOR THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-12-11 EP claimed
WO-2020022086-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION INCLUDING HETEROATOM IN POLYMER MAIN CHAIN 日産化学株式会社 2020-01-30 WO disclosed
EP-0306756-B1 OPTICAL ELEMENTS Geyer, Otto-Christian, Dr. (DE) 1993-02-03 EP disclosed
EP-0306756-A2 Optical elements Geyer, Otto-Christian, Dr. (DE) 1989-03-15 EP disclosed
EP-0114080-B1 POLYMERIZABLE LIQUID COMPOSITION ADAPTED TO PRODUCE POLYMERS HAVING OUTSTANDING OPTICAL AND MECHANICAL PROPERTIES, POLYMERS AND ARTICLES OBTAINED WITH SAID COMPOSITION ENICHEM SYNTHESIS S.p.A. (IT) 1988-03-30 EP disclosed
US-4521577-A Liquid polymerizable compositions of a carbonate oligomer, an allylcarbonate and vinyl acetate ENICHIMICA S.P.A. (IT) 1985-06-04 US disclosed
US-4272574-A Optically readable information disc U.S. PHILIPS CORPORATION (US) 1981-06-09 US disclosed