Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636630 | 1.00 | LMNA (0.49) | LMNACYP2D6CYP2C19CHRM2ADRA1A | |
| SCHEMBL3681375 | 0.82 | GAA (0.61) | LMNACYP2D6CYP2C19CHRM2ADRA1A | |
| SCHEMBL3681373 | 0.82 | GAA (0.61) | LMNACYP2D6CYP2C19CHRM2ADRA1A | |
| Bicarbonate SCHEMBL11119101 | 0.77 | BCHE (0.54) | NPSR1MEN1KMT2ABCHEOPRK1 | |
| SCHEMBL20144709 | 0.76 | GAA (0.62) | LMNACYP2D6CYP2C19CHRM2ADRA1A | |
| Ephedrine SCHEMBL28142813 | 0.75 | CYP2D6 (0.61) | LMNACYP2D6CYP2C19CHRM2ADRA1A | |
| Alifedrine SCHEMBL2108978 | 0.75 | SLC6A4 (0.49) | LMNACYP2D6CYP2C19CHRM2ADRA1A | |
| SCHEMBL8751273 | 0.75 | CYP1A2 (0.60) | LMNACYP2D6CYP2C19CHRM2ADRA1A | |
| SCHEMBL16067322 | 0.75 | NPC1 (0.52) | NPSR1MEN1KMT2ABCHEOPRK1 | |
| SCHEMBL11065754 | 0.75 | HTT (0.39) | CYP2D6HTTMEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193347-A1 | Using an optically active N-substituted chiral derivative of norephedrine as ligand for enantioselective reduction of unsaturated compounds carrying functional groups by a hydrogen transfer method | PPG-SIPSY, A CORPORATION OF FRANCE (FR) | 2002-12-19 | — | — | US | disclosed |