Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | SPOP | O43791 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636710 | 0.86 | NR1I2 (0.39) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL8882343 | 0.84 | KDM4E (0.39) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL8077885 | 0.84 | NR1I2 (0.42) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL9388602 | 0.83 | NR1I2 (0.38) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL10436335 | 0.79 | KDM4E (0.40) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL8718137 | 0.79 | KDM4E (0.39) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL10696803 | 0.78 | KDM4E (0.41) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL9198941 | 0.78 | SPOP (0.41) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL9190737 | 0.78 | KDM4E (0.41) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL10670083 | 0.77 | KDM4E (0.42) | NR1I2PGRPTGS2KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266060-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1988-05-04 | — | — | EP | disclosed |