Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | SPOP | O43791 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636710 | 0.86 | NR1I2 (0.39) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL8882343 | 0.84 | KDM4E (0.39) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL8077885 | 0.84 | NR1I2 (0.42) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL10693978 | 0.83 | NR1I2 (0.39) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL10436335 | 0.79 | KDM4E (0.40) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL8718137 | 0.79 | KDM4E (0.39) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL9190737 | 0.78 | KDM4E (0.41) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL10696803 | 0.78 | KDM4E (0.41) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL9198941 | 0.78 | SPOP (0.41) | NR1I2PGRPTGS2KDM4ETDP1 | |
| SCHEMBL10670083 | 0.77 | KDM4E (0.42) | NR1I2PGRPTGS2KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6092969-A | — | — | None | — | — | JP | disclosed |
| JP-H0692969-A | 7-ACYL-3-SUBSTITUTED CARBAMOYLOXYCEPHEM COMPOUND AND ITS PRODUCTION | EISAI CO LTD | 1994-04-05 | — | — | JP | disclosed |