SCHEMBL7636832

SCHEMBL7636832

C=CC1=CCc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1D P25100 3/20 0.37
ADRA1A P35348 3/20 0.37
ADRA1B P35368 1/20 0.37
HTR6 P50406 3/20 0.37
CES1 P23141 2/20 0.37
MAOA P21397 2/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP19A1 P11511 2/20 0.31
CYP11B2 P19099 2/20 0.31
MAOB P27338 2/20 0.31
CYP11B1 P15538 1/20 0.31
BCHE P06276 1/20 0.30
CYP1A2 P05177 2/20 0.30
ADRB2 P07550 2/20 0.30
RET P07949 2/20 0.30
CHRM2 P08172 2/20 0.30
CHRM4 P08173 2/20 0.30
ADRB1 P08588 2/20 0.30
HTR1A P08908 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4026269 0.86 ADRA1D (0.34) ADRA1DADRA1AADRA1BHTR6
SCHEMBL2863342 0.80 HTR6 (0.42) HTR6CES1MAOAALDH1A1MAOB
SCHEMBL27903942 0.79 HSD17B10 (0.42) CES1TSHRALDH1A1BCHECYP1A2
SCHEMBL11728305 0.78 HTR6 (0.37) ADRA1DADRA1AHTR6CES1MAOA
SCHEMBL27590862 0.78 HTR6 (0.37) HTR6CES1MAOAMAOBBCHE
SCHEMBL14672853 0.75 HTR6 (0.35) HTR6CES1MAOA
SCHEMBL14672854 0.75 HTR6 (0.35) HTR6CES1MAOA
SCHEMBL19750905 0.75 HTR6 (0.35) HTR6CES1MAOA
SCHEMBL29253926 0.74 ALDH1A1 (0.34) HTR6TSHRALDH1A1
SCHEMBL8678684 0.74 ALDH1A1 (0.39) MAOAALDH1A1CYP19A1CYP11B2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112105654-A Curable resin mixture, curable resin composition, and cured product thereof 日本化药株式会社 2020-12-18 CN disclosed
WO-2020031935-A1 CURABLE RESIN MIXTURE, CURABLE RESIN COMPOSITION, AND CURED PRODUCT 日本化薬株式会社 2020-02-13 WO disclosed
US-6372930-B1 POLYMERIC LIGAND HAVING UNITS CONTAINING AT LEAST ONE BRIDGED CYCLOPENTADIENYL-TYPE GROUP INCLUDING AT LEAST ONE FLUORENYL-TYPE GROUP PHILLIPS PETROLEUM COMPANY 2002-04-16 US disclosed
US-6124414-A POLYMERIC METALLOCENE CATALYST WHICH IS PREPARED BY POLYMERIZING A 2-VINYLFLUORENE OR BY REACTING FLUORENE COMPOUND WITH CHLOROMETHYLMETHYLETHER, REACTING THE POLYMER WITH ALKALI METAL AND THEN WITH TRANSITIONAL METAL COMPOUND PHILLIPS PETROLEUM COMPANY (US) 2000-09-26 US disclosed
US-6057410-A COMPLEXING FOR POLYMERIZATION CATALYSTS A PENTADIENYL LIGAND AND POLYMERIZATION WITH INITIATORS PHILLIPS PETROLEUM COMPANY (US) 2000-05-02 US disclosed
US-6040402-A PRODUCT OF REACTING A FLUORENYL-CONTAINING POLYMER WITH AN ALKALI METAL COMPOUND; AND REACTING THE PRODUCT OF STEP WITH A TRANSITION METAL-CONTAINING COMPOUND. PHILLIPS PETROLEUM COMPANY (US) 2000-03-21 US disclosed
US-5770755-A REACTION OF TRANSITION METAL COMPOUND WITH POLYMER CONTAINING CYCLOPENTADIENE, INDENE, OR FLUORENE GROUPS PHILLIPS PETROLEUM COMPANY (US) 1998-06-23 US disclosed