Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | PTPRF | P10586 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638695 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CASP1HSD17B10KMT2ACA1 | |
| SCHEMBL7635056 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CASP1HSD17B10KMT2ACA1 | |
| SCHEMBL7635753 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CASP1HSD17B10KMT2ACA1 | |
| SCHEMBL7636049 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CASP1HSD17B10KMT2ACA1 | |
| SCHEMBL7643253 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CASP1HSD17B10KMT2ACA1 | |
| SCHEMBL7940532 | 0.98 | ALDH1A1 (0.39) | ALDH1A1CASP1HSD17B10KMT2ACA1 | |
| SCHEMBL7636327 | 0.93 | ALDH1A1 (0.33) | ALDH1A1CASP1HSD17B10RXRA | |
| SCHEMBL7635786 | 0.76 | KMT2A (0.38) | ALDH1A1CASP1HSD17B10KMT2ACA1 | |
| SCHEMBL7942188 | 0.76 | KMT2A (0.38) | ALDH1A1CASP1HSD17B10KMT2ACA1 | |
| SCHEMBL7636295 | 0.76 | KMT2A (0.38) | ALDH1A1CASP1HSD17B10KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482966-B2 | REDUCING A CROSSLINK-CYCLIZED CYCLOPENTANONE WITH AN ALKALI METAL HYDRIDE, AND THEN REATING THE RESULTING CROSSLINK-CYCLIZED CYCLOPENTENOL IS WITH A DEHYDRATING AGENT | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| US-20010012902-A1 | Crosslink-cyclized cyclopentadiene and dihalobis type metal compound containing same as ligand | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-08-09 | — | — | US | disclosed |
| EP-1122229-A1 | Process for the preparation of condensed cyclopentadiene derivatives, 1, 3 disubstituted derivatives and metallocene type compounds containing them as ligand | HONSHU CHEMICAL INDUSTRY CO. LTD. (JP) | 2001-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010012902-A1 | Crosslink-cyclized cyclopentadiene and dihalobis type metal compound containing same as ligand | CYC1, DCLRE1A, PPIL1 | ALDH1A1 1309/4885CASP1 576/4885HSD17B10 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.