Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074646 | 1.00 | CASR (0.67) | CASRLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28846531 | 0.84 | HTT (0.55) | CASRLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23754499 | 0.84 | HTT (0.55) | CASRLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29864910 | 0.83 | MEN1 (0.68) | CASRLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23754498 | 0.83 | MEN1 (0.68) | CASRLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23754506 | 0.83 | MEN1 (0.68) | CASRLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2471237 | 0.81 | LMNA (0.64) | CASRLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7637536 | 0.80 | MEN1 (0.72) | CASRLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7637533 | 0.80 | MEN1 (0.72) | CASRLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3678237 | 0.80 | MEN1 (0.54) | CASRLMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102177132-B | Optically active vinylcyclopropanecarboxylic acid derivative and method for producing optically active vinylcyclopropaneamino acid derivative | KANEGAFUCHI CHEMICAL IND | 2014-06-25 | — | — | CN | disclosed |
| US-20110245529-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE VINYLCYCLOPROPANECARBOXYLIC ACID DERIVATIVE AND OPTICALLY ACTIVE VINYLCYCLOPROPANEAMINO ACID DERIVATIVE | KANEKA CORPORATION (JP) | 2011-10-06 | — | — | US | disclosed |
| EP-2345633-A1 | OPTICALLY ACTIVE VINYL-CYCLOPROPANE CARBOXYLIC ACID DERIVATIVE AND OPTICALLY ACTIVE VINYL-CYCLOPROPANE AMINO ACID DERIVATIVE MANUFACTURING METHOD | Kaneka Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245529-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE VINYLCYCLOPROPANECARBOXYLIC ACID DERIVATIVE AND OPTICALLY ACTIVE VINYLCYCLOPROPANEAMINO ACID DERIVATIVE | ALAD, AMD1, ADCY5 | CASR 2832/4885LMNA 1841/4885MEN1 3348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.