Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RNF4 | P78317 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637174 | 0.81 | CYP3A4 (0.47) | ALDH1A1GAA | |
| SCHEMBL7641484 | 0.81 | CYP19A1 (0.37) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL7641427 | 0.81 | IDH1 (0.44) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL7637990 | 0.77 | RNF4 (0.44) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL7637994 | 0.74 | RNF4 (0.41) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL2492138 | 0.74 | SLC6A2 (0.45) | MEN1KMT2AALDH1A1LMNAMTNR1A | |
| SCHEMBL7645535 | 0.73 | CYP3A4 (0.48) | ALDH1A1NPSR1GAA | |
| SCHEMBL9225377 | 0.73 | IDH1 (0.45) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL7644923 | 0.73 | CYP19A1 (0.38) | MEN1KMT2AALDH1A1LMNANPSR1 | |
| SCHEMBL3927370 | 0.71 | CA12 (0.41) | MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465650-B1 | INTERMEDIATE STEPS IN PREPARING PEPTIDE NUCLEIC ACIDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-10-15 | — | — | US | disclosed |
| US-6075143-A | USEFUL FOR FORMING PEPTIDE NUCLEIC ACIDS OR HYBRID OF PEPTIDE NUCLEIC ACIDS AND DEOXYNUCLEIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |