Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641427 | 0.93 | IDH1 (0.44) | IDH1KMT2AMEN1PTGS2ALDH1A1 | |
| SCHEMBL7644923 | 0.84 | CYP19A1 (0.38) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7645535 | 0.84 | CYP3A4 (0.48) | ALDH1A1NPSR1 | |
| SCHEMBL3927370 | 0.77 | CA12 (0.41) | KMT2AMEN1HPGDKEAP1NFE2L2 | |
| SCHEMBL7641484 | 0.77 | CYP19A1 (0.37) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7637174 | 0.77 | CYP3A4 (0.47) | ALDH1A1 | |
| SCHEMBL7637993 | 0.73 | MEN1 (0.48) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7641429 | 0.70 | IDH1 (0.37) | IDH1KMT2AMEN1PTGS2ALDH1A1 | |
| SCHEMBL2492138 | 0.68 | SLC6A2 (0.45) | KMT2AMEN1ALDH1A1LMNATDP1 | |
| SCHEMBL3927386 | 0.65 | SLC6A2 (0.42) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672661-A1 | Substituted N-ethyl-glycinderivatives for the preparation of PNA and PNA-/DNA hybrides | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-20 | — | — | EP | disclosed |