Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645535 | 0.93 | CYP3A4 (0.48) | CYP3A4CYP2D6HMOX2CYP19A1ALDH1A1 | |
| SCHEMBL7641484 | 0.84 | CYP19A1 (0.37) | CYP19A1ALDH1A1MAPK1 | |
| SCHEMBL7641427 | 0.84 | IDH1 (0.44) | ALDH1A1KDM4E | |
| SCHEMBL7637169 | 0.81 | CYP3A4 (0.48) | CYP3A4CYP2D6HMOX2CYP19A1ALDH1A1 | |
| SCHEMBL7637993 | 0.81 | MEN1 (0.48) | ALDH1A1GAA | |
| SCHEMBL7637178 | 0.78 | CYP19A1 (0.43) | CYP19A1ALDH1A1GAAMAPK1L3MBTL1 | |
| SCHEMBL7639309 | 0.78 | TK1 (0.40) | MAPK1 | |
| SCHEMBL9225377 | 0.77 | IDH1 (0.45) | ALDH1A1 | |
| SCHEMBL7644923 | 0.77 | CYP19A1 (0.38) | CYP19A1ALDH1A1 | |
| SCHEMBL7645531 | 0.76 | CYP3A4 (0.49) | CYP3A4CYP2D6HMOX2CYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465650-B1 | INTERMEDIATE STEPS IN PREPARING PEPTIDE NUCLEIC ACIDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-10-15 | — | — | US | disclosed |
| US-6075143-A | USEFUL FOR FORMING PEPTIDE NUCLEIC ACIDS OR HYBRID OF PEPTIDE NUCLEIC ACIDS AND DEOXYNUCLEIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-06-13 | — | — | US | disclosed |
| EP-0672661-A1 | Substituted N-ethyl-glycinderivatives for the preparation of PNA and PNA-/DNA hybrides | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-20 | — | — | EP | disclosed |