Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.56 |
| ▸ | DNM2 | P50570 | 10/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20434304 | 0.81 | TLR8 (0.65) | TLR8ALDH1A1LMNATSHR | |
| SCHEMBL30263108 | 0.80 | TLR8 (0.64) | TLR8DNM2SOAT1 | |
| SCHEMBL29156884 | 0.80 | TLR8 (0.64) | TLR8DNM2SOAT1 | |
| SCHEMBL2990823 | 0.79 | CDK1 (0.46) | TLR8NUDT1MEN1ALDH1A1LMNA | |
| SCHEMBL5791298 | 0.79 | TLR8 (0.88) | TLR8DNM2MEN1ALDH1A1LMNA | |
| SCHEMBL7117794 | 0.78 | CYP2D6 (0.62) | TLR8DNM2ALDH1A1KMT2A | |
| SCHEMBL7118699 | 0.78 | CYP2D6 (0.62) | TLR8DNM2ALDH1A1KMT2A | |
| SCHEMBL7135338 | 0.78 | CYP2D6 (0.62) | TLR8DNM2ALDH1A1KMT2A | |
| SCHEMBL7124897 | 0.78 | CYP2D6 (0.62) | TLR8DNM2ALDH1A1KMT2A | |
| SCHEMBL16703349 | 0.78 | CYP2D6 (0.62) | TLR8DNM2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455054-B2 | THERAPY FOR SKIN DISORDERS | SOCIETE L'OREAL S.A. (FR) | 2002-09-24 | — | — | US | disclosed |