Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10398846 | 0.90 | CDK1 (0.43) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL2987423 | 0.89 | ALDH1A1 (0.46) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL10620415 | 0.84 | ALDH1A1 (0.41) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL4564977 | 0.83 | NUDT1 (0.58) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL31403787 | 0.82 | ALDH1A1 (0.45) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL4264141 | 0.81 | MEN1 (0.43) | RAB9AALDH1A1NPC1TLR8POLB | |
| SCHEMBL9340530 | 0.81 | CDK1 (0.43) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL1576650 | 0.80 | NPC1 (0.62) | RAB9AALDH1A1NPC1MAPK1NUDT1 | |
| SCHEMBL7638429 | 0.79 | TLR8 (0.56) | ALDH1A1NUDT1TLR8POLBLMNA | |
| SCHEMBL27849505 | 0.79 | GLA (0.42) | RAB9AALDH1A1NPC1TLR8POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102285925-A | Synthesis method of 2-chloro-4,6-dibutoxypyrimidine | — | 2011-12-21 | — | — | CN | disclosed |
| US-7781582-B2 | Process for the preparation of 2-amino-[1,2,4]triazolo[1,5-a]pyrimidines | DOW AGROSCIENCES LLC (US) | 2010-08-24 | — | — | US | disclosed |
| EP-1699794-B1 | PROCESS FOR THE PREPARATION OF TRIAZOLOPYRIMIDINES | DOW AGROSCIENCES LLC (US) | 2008-01-02 | — | — | EP | disclosed |
| US-20070238873-A1 | Process for the Preparation of Triazolopyrimidines | CORTEVA AGRISCIENCE LLC | 2007-10-11 | — | — | US | disclosed |
| EP-1699794-A1 | PROCESS FOR THE PREPARATION OF TRIAZOLOPYRIMIDINES | Dow AgroSciences LLC (US) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005063753-A1 | PROCESS FOR THE PREPARATION OF TRIAZOLOPYRIMIDINES | DOW AGROSCIENCES LLC (US) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238873-A1 | Process for the Preparation of Triazolopyrimidines | NUDT1, ABL1, DPYD | CDK1 447/4885CCNB1 337/4885CCNA2 1000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.