Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643237 | 0.86 | MAPT (0.37) | ESR1ALOX15SMN1; SMN2LMNAMAPT | |
| SCHEMBL10892516 | 0.84 | ESR1 (0.51) | ESR1ALOX15MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL7638488 | 0.84 | MAPT (0.46) | SMN1; SMN2LMNAMAPTHTTMEN1 | |
| SCHEMBL9872251 | 0.84 | CYP3A4 (0.45) | ALOX15SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL23611519 | 0.82 | ALOX15 (0.50) | ESR1ALOX15MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL7636019 | 0.82 | TSHR (0.43) | ESR1SMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL245816 | 0.82 | MTNR1A (0.51) | ESR1ALOX15MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL309045 | 0.81 | MTNR1A (0.50) | ESR1ALOX15MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL17685579 | 0.81 | ESR1 (0.51) | ESR1ALOX15MTNR1AMTNR1BSMN1; SMN2 | |
| Water SCHEMBL28663040 | 0.81 | MTNR1A (0.50) | ESR1ALOX15MTNR1AMTNR1BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6464734-B1 | USED FOR DYEING OR PRINTING HYDROXYL AND/OR CARBOXAMIDO CONTAINING MATERIALS SUCH AS POLYVINYL ALCOHOL, POLYURETHANES AND POLYAMIDES; WASHFASTNESS | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-10-15 | — | — | US | disclosed |
| EP-1134260-A1 | Deep black dye mixtures of fiber-reactive azo dyes | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2001-09-19 | — | — | EP | disclosed |
| US-4582897-A | 2-AZO-4-SULFO-4-METHYLDIPHENYL SULFONE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |