Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17141368 | 0.80 | TSHR (0.41) | TSHRPARP1GSTO1CHRM2CHRM4 | |
| SCHEMBL46283 | 0.77 | TSHR (0.67) | TSHRPARP1GSTO1PTPN1ALOX5 | |
| SCHEMBL14753779 | 0.76 | GSTO1 (0.40) | TSHRPARP1GSTO1CHRM2CHRM4 | |
| SCHEMBL14749897 | 0.76 | PARP1 (0.41) | TSHRPARP1GSTO1CHRM2DRD3 | |
| SCHEMBL16641133 | 0.75 | TSHR (0.39) | TSHRPARP1GSTO1 | |
| SCHEMBL37732 | 0.71 | TSHR (0.57) | TSHRPARP1CHRM2ADRA2ACHRM4 | |
| SCHEMBL16641062 | 0.71 | TSHR (0.38) | TSHR | |
| SCHEMBL24424975 | 0.70 | TSHR (0.55) | TSHRPARP1GSTO1PTPN1ALOX5 | |
| SCHEMBL871294 | 0.70 | TSHR (0.55) | TSHRPARP1GSTO1PTPN1ALOX5 | |
| SCHEMBL4296907 | 0.70 | ALOX5 (0.62) | TSHRPARP1GSTO1PTPN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362264-B1 | MIXTURE CONTAINING ZINC CARBOXYLATE, THIODIPROPIONIC ACID AND PHENOLIC ANTIOXIDANT | CK WITCO CORPORATION | 2002-03-26 | — | — | US | disclosed |
| EP-0849314-A1 | Stabilizer for food contact and medical grade PVC | WITCO CORPORATION (US) | 1998-06-24 | — | — | EP | disclosed |
| US-4348308-A | IMPROVING COLOR STABILITY OF VINYL CHLORIDE POLYMERS | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1982-09-07 | — | — | US | disclosed |
| US-4282141-A | DISCOLORATION INHIBITION FOR VINYL CHLORIDE POLYMERS | ARGUS CHEMICAL CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| EP-0028268-A1 | Stabilizer composition comprising a thio-1,3-dicarbonyl compound and a heat stabilizer, and vinyl halide polymer composition stabilized therewith | S.A. Diamond Shamrock Benelux N.V. (BE) | 1981-05-13 | — | — | EP | disclosed |
| US-4252698-A | A OVERBASED SULFONATE OR PHENOLATE, AND A 1,3-DIKETONE FOR VINYL CHLORIDE POLYMERS | ARGUS CHEMICAL CORPORATION (US) | 1981-02-24 | — | — | US | disclosed |
| US-4221687-A | BASIC INORGANIC SALT, 1,3-DIKETONE, VINYL CHLORIDE POLYMER | ARGUS CHEMICAL CORP. (US) | 1980-09-09 | — | — | US | disclosed |
| US-4217258-A | THIOCARBONYL COMPOUND, ALKYLTIN COMPOUND, METAL CARBOXYLATE, HYDROCARBYLPHENOL | ARGUS CHEMICAL CORP. (US) | 1980-08-12 | — | — | US | disclosed |