Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639009 | 0.87 | AKR1C3 (0.55) | ALDH1A1GAAMAPTAKR1C3MEN1 | |
| SCHEMBL6835473 | 0.84 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MAPTALOX15TSHR | |
| SCHEMBL7416476 | 0.82 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTTSHRBCHE | |
| SCHEMBL6048203 | 0.82 | LMNA (0.39) | ALDH1A1SMN1; SMN2MAPTALOX15BCHE | |
| SCHEMBL2945577 | 0.82 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTTP53ALOX15 | |
| SCHEMBL7606289 | 0.78 | LMNA (0.57) | ALDH1A1SMN1; SMN2GAAMAPTTP53 | |
| SCHEMBL5074597 | 0.77 | CYP3A4 (0.35) | ALDH1A1SMN1; SMN2ALOX15TSHRBCHE | |
| SCHEMBL38132 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2GAAMAPTTP53 | |
| SCHEMBL9352271 | 0.74 | NR4A2 (0.50) | ALDH1A1SMN1; SMN2GAAALOX15TSHR | |
| SCHEMBL8565728 | 0.73 | ADRA1A (0.39) | ALDH1A1TSHRBCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110027195-A1 | COMPOSITION FOR DENTAL BARRIER COMPRISING AT LEAST ONE MONOMER, AT LEAST ONE POLYMERIZATION INITIATING SYSTEM, AND AT LEAST ONE INDICATOR ENABLING THE POLYMERIZATION REACTION TO BE MONITORED | PRODUITS DENTAIRES PIERRE ROLLAND (FR) | 2011-02-03 | — | — | US | disclosed |