Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7633904 | 0.88 | NTRK1 (0.31) | NTRK1NTRK3TSHRHSD17B10USP2 | |
| SCHEMBL7941876 | 0.83 | NTRK1 (0.32) | NTRK1NTRK3TSHRHSD17B10USP2 | |
| Hydrochloric Acid SCHEMBL2525982 | 0.83 | PDCD1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL29564499 | 0.83 | PDCD1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7639506 | 0.81 | — | — | |
| Fluoride Ion SCHEMBL7636064 | 0.80 | PDCD1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL7935429 | 0.80 | ADRA2A (0.33) | — | |
| Hydrochloric Acid SCHEMBL21980378 | 0.80 | PDCD1 (0.33) | HTR2BTMEM97 | |
| Hydrochloric Acid SCHEMBL6553574 | 0.79 | PDCD1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8633266 | 0.77 | PDCD1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020098973-A1 | Bridged gallium or indium containing group 4 metal complexes | CAMPBELL RICHARD E (US) | 2002-07-25 | — | — | US | disclosed |