SCHEMBL8036025

SCHEMBL8036025

Cc1cc2ccc(=O)oc2cc1C

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.62
MCL1 Q07820 6/20 0.60
CA9 Q16790 10/20 0.59
CA12 O43570 8/20 0.59
KDM4E B2RXH2 6/20 0.59
HSD17B10 Q99714 6/20 0.59
AKR1B1 P15121 5/20 0.59
GAA P10253 5/20 0.59
HPGD P15428 5/20 0.59
GLA P06280 4/20 0.59
ACHE P22303 3/20 0.59
CASP1 P29466 3/20 0.59
CASP7 P55210 3/20 0.59
ERAP1 Q9NZ08 3/20 0.59
CYP1A2 P05177 3/20 0.59
CYP3A4 P08684 2/20 0.59
HIF1A Q16665 2/20 0.59
LMNA P02545 1/20 0.59
BCHE P06276 1/20 0.59
MAPT P10636 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4545214 0.84 CA9 (0.72) ALDH1A1MCL1CA9CA12KDM4E
SCHEMBL7759685 0.84 ALDH1A1 (0.55) ALDH1A1MCL1CA9CA12KDM4E
SCHEMBL27678755 0.84 CA9 (0.72) ALDH1A1MCL1CA9CA12KDM4E
SCHEMBL16722817 0.84 ALDH1A1 (0.55) ALDH1A1MCL1CA9CA12KDM4E
SCHEMBL16722819 0.84 ALDH1A1 (0.55) ALDH1A1MCL1CA9CA12KDM4E
SCHEMBL8750127 0.83 ALDH1A1 (0.53) ALDH1A1MCL1CA9CA12KDM4E
SCHEMBL8750119 0.83 ALDH1A1 (0.53) ALDH1A1MCL1CA9CA12KDM4E
SCHEMBL15843028 0.81 GAA (0.58) ALDH1A1MCL1CA9CA12KDM4E
SCHEMBL20416970 0.81 GAA (0.58) ALDH1A1MCL1CA9CA12KDM4E
SCHEMBL10205492 0.81 ALDH1A1 (0.51) ALDH1A1MCL1CA9CA12KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9127092-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2015-09-08 US claimed
US-20140187725-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2014-07-03 US claimed
US-5639893-A Process for producing octahydrocoumarins and same as a product of such process SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-17 US claimed
EP-0757989-A1 A process for producing octahydrocoumarins and same as a product of such process SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-02-12 EP claimed
US-11731960-B2 Biheterocyclic compound Sumitomo Pharma Co., Ltd. (JP) 2023-08-22 US disclosed
EP-3597673-B1 PHOTOCROSSLINKABLE POLYMER, INSULATING FILM, PLANARIZATION FILM, LYOPHILIC/LIQUID REPELLENT PATTERNED FILM, AND ORGANIC FIELD EFFECT TRANSISTOR DEVICE COMPRISING SAME TOSOH CORP (JP) 2023-06-07 EP disclosed
CN-112336758-B A bupleuri radix extract composition, and its preparation method and application in relieving convulsion 山西大学 2022-09-20 CN disclosed
CN-114617138-A Preparation method of mosquito repellent liquid extracted from environmentally-maintained long-lasting plants 四川盟达谊家环保科技有限公司 2022-06-14 CN disclosed
CN-113023905-A Plant fermentation extract for adjusting fresh water quality and preparation method thereof 北京局气网络技术有限公司 2021-06-25 CN disclosed
US-20210135115-A1 PHOTOCROSSLINKABLE POLYMER, INSULATING FILM, PLANARIZATION FILM, LYOPHILIC/LIQUID REPELLENT PATTERNED FILM, AND ORGANIC FIELD EFFECT TRANSISTOR DEVICE COMPRISING SAME TOSOH CORPORATION (JP) 2021-05-06 US disclosed
CN-112336758-A A bupleuri radix extract composition, and its preparation method and application in relieving convulsion 山西大学 2021-02-09 CN disclosed
CN-111689812-A Plant fermentation extract for improving potato planting and preparation method thereof 河北苏同兴盛新能源科技有限公司 2020-09-22 CN disclosed
WO-2010046240-A1 SULFONIUM DERIVATIVES AND THE USE THEROF AS LATENT ACIDS BASF SE (DE) 2010-04-29 WO disclosed
WO-2009150074-A1 SULFONIUM DERIVATIVES AND THE USE THEREOF AS LATENT ACIDS BASF SE (DE) 2009-12-17 WO disclosed
US-20070123690-A1 Conjugated polymers, representation thereof, and use of the same MERCK PATENT GMBH (DE) 2007-05-31 US disclosed
US-20070123690-A1 Conjugated polymers, representation thereof, and use of the same MERCK PATENT GMBH (DE) 2007-05-31 US disclosed
WO-2000076990-A1 NEW COMPOUNDS ASTRAZENECA AB (SE) 2000-12-21 WO disclosed
US-5639893-A Process for producing octahydrocoumarins and same as a product of such process SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-17 US disclosed
EP-0757989-A1 A process for producing octahydrocoumarins and same as a product of such process SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed
US-4441969-A ARYL HYDROXY CARBOXYLIC ACID OMI INTERNATIONAL CORPORATION (US) 1984-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731960-B2 Biheterocyclic compound NR4A3, NGF, OGFR ALDH1A1 3217/4885MCL1 2278/4885CA9 3291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.