Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640183 | 0.90 | ATM (0.40) | ATMKIF11CTSKCTSLCTSS | |
| SCHEMBL6419860 | 0.82 | ATM (0.47) | ATMKIF11CTSKCTSLCTSS | |
| SCHEMBL6419865 | 0.73 | ATM (0.47) | ATMKIF11CTSKCTSLCTSS | |
| SCHEMBL6422502 | 0.73 | CTSK (0.49) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL10425602 | 0.69 | ATM (0.62) | ATMCTSKCTSLCTSSCA1 | |
| SCHEMBL5898328 | 0.68 | ATM (0.60) | ATMCTSKCTSLCTSSCA1 | |
| SCHEMBL11816446 | 0.66 | ATM (0.67) | ATMCTSKCTSLCTSSCA1 | |
| SCHEMBL10441764 | 0.66 | ATM (0.67) | ATMCTSKCTSLCTSSCA1 | |
| SCHEMBL14878516 | 0.66 | ATM (0.50) | ATMCTSKCTSLCTSSCA1 | |
| SCHEMBL4725142 | 0.66 | ATM (0.67) | ATMCTSKCTSLCTSSCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165569-A1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | Agilent Technologies, Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056740-A1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | PROLINX, INC. (US) | 2000-09-28 | — | — | WO | disclosed |