Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420337 | 0.76 | CTSL (0.54) | ATMCA2CTSLCTSSCTSK | |
| SCHEMBL21890679 | 0.74 | TRPM8 (0.60) | ATMCA1CA2CTSLCTSS | |
| SCHEMBL20299924 | 0.74 | TRPM8 (0.60) | ATMCA1CA2CTSLCTSS | |
| SCHEMBL31563025 | 0.73 | ATM (0.61) | ATMCA1CA2ACHECTSL | |
| SCHEMBL7639360 | 0.73 | ATM (0.42) | ATMKIF11CA1CA2ACHE | |
| SCHEMBL28892051 | 0.72 | TRPM8 (0.62) | ATMCA2CTSLCTSSCTSK | |
| SCHEMBL10535601 | 0.72 | TRPM8 (0.62) | ATMCA2CTSLCTSSCTSK | |
| SCHEMBL10535596 | 0.72 | TRPM8 (0.62) | ATMCA2CTSLCTSSCTSK | |
| SCHEMBL6419860 | 0.72 | ATM (0.47) | ATMKIF11CA1CA2ACHE | |
| SCHEMBL4245909 | 0.72 | ATM (0.57) | ATMCA1CA2ACHECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165569-B1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES INC (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1165569-A1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | Agilent Technologies, Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056740-A1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | PROLINX, INC. (US) | 2000-09-28 | — | — | WO | disclosed |
| US-6031117-A | Boronic acid containing phosphoramidite reagents | PROLINX INCORPORATED (US) | 2000-02-29 | — | — | US | disclosed |
| US-6013783-A | Boronic acid containing oligonucleotides and polynucleotides | PROLINX INCORPORATED (US) | 2000-01-11 | — | — | US | disclosed |