Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634558 | 1.00 | TSHR (0.51) | TSHRGAAHPGDCYP1A2HDAC6 | |
| SCHEMBL7637320 | 0.86 | THRA (0.43) | TSHRGAAHPGDCYP1A2HDAC6 | |
| SCHEMBL7634258 | 0.85 | POLR1A (0.45) | TSHRGAAHPGDCYP1A2HDAC6 | |
| SCHEMBL10357466 | 0.82 | TSHR (0.50) | TSHRGAAHPGDCYP1A2HDAC6 | |
| SCHEMBL8964075 | 0.82 | TSHR (0.50) | TSHRGAAHPGDCYP1A2HDAC6 | |
| SCHEMBL5311374 | 0.81 | MCHR1 (0.46) | TSHRGAAHPGDCYP1A2TP53 | |
| SCHEMBL8202747 | 0.80 | CHRM2 (0.48) | TSHRGAAHPGDCYP1A2HDAC6 | |
| SCHEMBL10330500 | 0.80 | KMT2A (0.58) | TSHRGAAHPGDCYP1A2HDAC6 | |
| SCHEMBL9091405 | 0.79 | TSHR (0.48) | TSHRGAAHPGDCYP1A2HDAC6 | |
| SCHEMBL8963512 | 0.79 | TSHR (0.48) | TSHRGAAHPGDCYP1A2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911320-B1 | 1,2-Di-substituted benzenecarboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-6114325-A | 1,2-di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| CN-1224712-A | 1,2-Di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 1999-08-04 | — | — | CN | disclosed |
| EP-0911320-A2 | 1,2-Di-substituted benzenecarboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 1999-04-28 | — | — | EP | disclosed |