Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 11/20 | 0.43 |
| ▸ | THRB | P10828 | 10/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204132 | 0.96 | TSHR (0.44) | THRATHRBTSHRCYP1A2GAA | |
| SCHEMBL7634705 | 0.87 | TSHR (0.42) | THRATHRBTSHRCYP1A2GAA | |
| SCHEMBL7634558 | 0.86 | TSHR (0.51) | TSHRCYP1A2GAAHPGDLMNA | |
| SCHEMBL7639416 | 0.86 | TSHR (0.51) | TSHRCYP1A2GAAHPGDLMNA | |
| SCHEMBL7638368 | 0.84 | THRB (0.43) | THRATHRBALDH1A1KDM4E | |
| SCHEMBL7641083 | 0.81 | LMNA (0.43) | THRATHRBTSHRCYP1A2GAA | |
| SCHEMBL7634258 | 0.81 | POLR1A (0.45) | TSHRCYP1A2GAAHPGDLMNA | |
| SCHEMBL7637361 | 0.80 | HTT (0.50) | THRATHRBTSHRHPGDALDH1A1 | |
| SCHEMBL8205114 | 0.79 | KDM4E (0.45) | THRATHRBCYP1A2ALDH1A1MAPK1 | |
| SCHEMBL8194371 | 0.78 | DNM1 (0.42) | THRATHRBTSHRCYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911320-B1 | 1,2-Di-substituted benzenecarboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 2002-07-24 | — | — | EP | disclosed |
| EP-0911320-A2 | 1,2-Di-substituted benzenecarboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 1999-04-28 | — | — | EP | disclosed |