Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639635 | 1.00 | NFE2L2 (0.44) | NFE2L2PTGS2MEN1POLBKMT2A | |
| SCHEMBL15364425 | 0.87 | ALDH1A1 (0.47) | MEN1POLBKMT2ANPC1MAPT | |
| SCHEMBL15364420 | 0.87 | ALDH1A1 (0.47) | MEN1POLBKMT2ANPC1MAPT | |
| SCHEMBL26156777 | 0.69 | TRPA1 (0.50) | NFE2L2PTGS2MEN1KMT2ATRPA1 | |
| SCHEMBL2622602 | 0.69 | NFE2L2 (0.61) | NFE2L2TRPA1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6937636 | 0.69 | ESR1 (0.36) | MEN1POLBKMT2AL3MBTL1NPC1 | |
| SCHEMBL12750946 | 0.67 | CYP3A4 (0.35) | — | |
| SCHEMBL15364362 | 0.67 | GAA (0.43) | MEN1POLBKMT2APKML3MBTL1 | |
| SCHEMBL6170114 | 0.67 | MEN1 (0.62) | PTGS2MEN1POLBKMT2ANPC1 | |
| SCHEMBL6170117 | 0.67 | MEN1 (0.62) | PTGS2MEN1POLBKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455720-B1 | AS CATALYSTS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-09-24 | — | — | US | disclosed |