SCHEMBL7639657

SCHEMBL7639657

CCC(C)(C)c1cc(C(C)(C)CC)c(OC(c2c(C(C)(C)CC)cc(C(C)(C)CC)cc2C(C)(C)CC)C(CO)(CO)CO)c(C(C)(C)CC)c1.OP(O)O.OP(O)O

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RXRA P19793 5/20 0.35
PPARG P37231 5/20 0.35
RARG P13631 4/20 0.35
RARA P10276 1/20 0.32
RARB P10826 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7639654 0.89 RXRA (0.34) RXRAPPARGRARGRARARARB
SCHEMBL995221 0.85
SCHEMBL1074119 0.80 RXRA (0.31) RXRAPPARGRARGRARARARB
SCHEMBL25435252 0.76
SCHEMBL674846 0.75 CYP3A4 (0.35) SMN1; SMN2
SCHEMBL29139883 0.75 HSPA5 (0.37) MEN1ALDH1A1MAPK1KMT2ANPSR1
SCHEMBL11025710 0.75 HSPA5 (0.37) MEN1ALDH1A1MAPK1KMT2ANPSR1
SCHEMBL379576 0.75 RXRA (0.33) RXRAPPARGRARGRARARARB
SCHEMBL313283 0.74 SMN1; SMN2 (0.36) ALDH1A1SMN1; SMN2
SCHEMBL192004 0.74 SMN1; SMN2 (0.36) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0856526-B1 OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PRODUCING THE SAME, CATALYST FOR (CO)POLYMERIZING OLEFIN, AND PROCESS FOR PRODUCING THE SAME CHISSO CORP (JP) 2002-08-28 EP disclosed
US-6313225-B2 High melt tension, high crystallization temperature; hollow moldings CHISSO CORPORATION (JP) 2001-11-06 US disclosed
US-20010004657-A1 OLEFIN(CO-) POLYMER COMPOSITIONS AND METHOD FOR PRODUCING THE SAME ANDCATALYST FOR OLEFIN (CO-) POLYMERIZATION AND METHOD FOR PRODUCING THE SAME CHISSO CORPORATION (JP) 2001-06-21 US disclosed
US-6231804-B1 USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER CHISSO CORPORATION (JP) 2001-05-15 US disclosed
US-6156845-A Polyolefin composition and method of making CHISSO CORPORATION (JP) 2000-12-05 US disclosed
EP-0972800-A1 MODIFIED OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PREPARING THE SAME, AND MODIFIED OLEFIN (CO)POLYMER COMPOSITION MOLDING CHISSO CORPORATION (JP) 2000-01-19 EP disclosed
EP-0856526-A1 OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PRODUCING THE SAME, CATALYST FOR (CO)POLYMERIZING OLEFIN, AND PROCESS FOR PRODUCING THE SAME CHISSO CORPORATION (JP) 1998-08-05 EP disclosed