Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.66 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TST | Q16762 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637549 | 0.93 | HTR2A (0.56) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL28827751 | 0.85 | HTR2A (0.56) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL24021959 | 0.85 | HTR2A (0.56) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL6182941 | 0.85 | TAAR1 (0.54) | HTR2AESR1KDM4EALDH1A1LPL | |
| SCHEMBL23522328 | 0.82 | TAAR1 (0.47) | HTR2AESR1TAAR1S1PR1S1PR3 | |
| SCHEMBL23241044 | 0.82 | HTR2A (0.53) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL12502918 | 0.82 | HTR2A (0.66) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL11664454 | 0.82 | HTR2A (0.66) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9945668 | 0.81 | HTR2A (0.60) | HTR2AESR1ADRA2AADORA3TACR2 | |
| SCHEMBL1313200 | 0.81 | HTR2A (0.60) | HTR2AESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479456-B1 | PERFUMED PRODUCTS (SUCH AS BODY CARE PRODUCTS, DETERGENTS ETC.) NOT ONLY GIVES OFF PLEASANT ODOR, BUT INCREASES, SYNERGISTICALLY, THE ANTIMICROBIAL ACTVITY; GRAPEFRUIT-PIT EXTRACT, FUMITORY EXTRACT, FUMARIC ACID, OR IT'S ESTER | FIRMENICH SA (CH) | 2002-11-12 | — | — | US | disclosed |